Motor Control: How Does a Cancer Cell Power its Movement?

This image, captured by a team of researchers at the Koch Institute and Massachusetts General Hospital, shows a microscopic device for analyzing how cancer cells move and migrate in the body.

Salil Desai, Sangeeta Bhatia, Mehmet Toner and Daniel Irimia
Center for Engineering in Medicine, Massachusetts General Hospital; Koch Institute
Epi-Fluorescence and Phase Contrast Micrograph

Much of the deadly impact of cancer is due to metastasis, the spread of cancer cells to distant tissues.  But what drives a cancer cell’s movementthrough the body?  Here, researchers investigate the role of mitochondria, the “powerhouses” inside cancer cells, as the cells travel through tiny fluid-filled channels.

Salil Desai explains how and why he took this image of cancer cells moving through microscopic channels.