Macrophage Trampoline: Immune Cells Attack Therapeutic Devices

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Submitted by Andrew R. Bader, Omid Veiseh, and Arturo Vegas of the Anderson Laboratory at the Koch Institute for Integrative Cancer Research at MIT

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This is a large spherical capsule made out of seaweed-based polymers, designed to hold and deliver all sorts of payloads including therapeutic drugs. The immune cells of the host body recognized the presence of the foreign sphere and deposited a red fibrotic coating around the capsule. The green spots are the macrophage cells that are sensing the capsules.