Nanoparticles Target Endothelial Cells

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Submitted by Aude Thiriot and James Dahlman from the laboratories of Daniel G. Anderson (Koch Institute at MIT), Robert Langer (Koch Institute at MIT), and Ulrich H. von Andrian (Harvard Medical School)

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Nanoparticles (in red) can be designed to effectively and specifically deliver drugs to the endothelial cells that line your blood vessels (in blue). This image, of blood vessels in a mouse, was taken in order to learn whether our endothelial-targeting nanoparticles delivered drugs to these cells in vivo. The nanoparticles pictured are in consideration for clinical trials in lung cancer and heart disease.