Porous Microspheres for Drug Delivery

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Submitted by Stephany Y. Tzeng with Ana Jaklenec and Robert Langer of the Koch Institute for Integrative Cancer Research


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Microspheres with high porosity can be loaded with a protein or any other drug and then sealed to prevent leakage of the drug from the microspheres. This method can replace or complement traditional methods of encapsulating a drug within a microsphere, with the advantage that the drug of interest does not have to be exposed to the relatively harsh processing conditions necessary for microsphere formation. This image shows porous microspheres made out of a biodegradable polymer for use as a drug carrier.