Central Nervous System Tissue Model

Central Nervous System Tissue Model

Collin Edington and Iris Lee

MIT Department of Biological Engineering, Koch Institute at MIT

The image shows a mix of different brain cell types, including glial cells (red) and neurons (green) differentiated from neural progenitor cells. Multipotent neural stem cells are shown in yellow and cell nuclei are shown in blue.  The Central Nervous System (CNS) model was matured for 3 weeks in a bioreactor containing tissue models of 6 additional human organ systems (gut, lung, liver, heart, pancreas, and endometrium), allowing each organ to communicate chemically with the others to recreate the complex inter-organ signaling of the human body.

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