Lymphocytes Infiltrate Melanoma Cells 2

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Kelly Moynihan

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These H&E images depict melanomas undergoing immunotherapy treatment. The images show high infiltration of lymphocytes, the immune system’s effector cells against tumors, in a mouse melanoma model that is considered very challenging. In this images, swarms of lymphocytes can be identified by their small, dense nuclei, and pockets of brown melanin produced by the tumor can be seen throughout.