Examining Organoids, Image 3

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Marit van Gorsel, Daniel Schmidt, Matthew Vander Heiden

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These pictures all show normal mouse prostate organoids, 3D spheres of cells that grow in a culture dish. We took these images to keep track and to study the phenotype of these organoids. The H&E stained organoids (first picture), gives a beautiful insight in their structure. The organoid culture system allows us to culture normal prostate cells, which is very hard in 2D tissue culture. Since this is such a new culture system, it was very important to get to know the behavior and the structure of these organoids.