Blood Vessel Architecture in a Breast Tumor

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Submitted by Alex Bagley of the Laboratory for Multiscale Regenerative Technologies at the Koch Institute

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Alex Bagley, Sangeeta Bhatia
Laboratory for Multiscale Regenerative Technologies, Koch Institute
Optical Frequency Domain Imaging

"This image was taken in a live subject, and depicts blood vessel architecture in a sample of human breast cancer grown in an animal host (called a xenograft).  We were quantitatively comparing differences in tumor microvascular architecture as a function of tumor type and site of implantation. Here, we discovered that breast xenografts display a more complex and extensive vascular network than ovarian tumor nodules in the peritoneal cavity."