Cellularization in a Wild-Type and Mutant Fruit Fly Embryo

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Submitted by Claudia Vasquez of the Martin Lab in the Department of Biology

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Claudia Vasquez
Martin Lab, Department of Biology
Confocal Micrograph

"This image shows cellularization -- the event just before ventral furrow formation in Drosophila melanogaster embryo development.  During celullarization the cell membrane forms apically around the syncytial nuclei and extends down towards the basal ends of the cells. In this image there are two embryos: the embryo on top has a wild-type version of the myosin regulatory light chain (RLC) tagged with GFP while the bottom embryo has a constitutively active version of the RLC tagged with GFP.  I took the image to see if mutations to the RLC had effects on the embryo's development before the ventral furrow."