Mosaic of Cilia Growth in Human Airway Epithelial Cells


Submitted by Brett Zani of the Edelman Lab in the Harvard-MIT Division of Health Sciences and Technology and the MIT Koch Institute


Brett Zani
Edelman Lab, Harvard-MIT Division of Health Sciences and Technology & MIT Koch Institute
Epi-Fluorescence Micrograph

"A cellular mosaic is created by the actin cytoskeleton (red), tubulin cytoskeleton (green), and nuclei (blue) of primary human airway epithelial cells grown on an air-liquid interface. The air-liquid interface allows the airway epithelial cells to be grown exposed to air resulting in a distinct cellular morphology that is similar to native airway epithelium in the body. This cellular morphology is not observed when cells are immersed in cell media. The vibrant green areas show where cilia have sprouted out from epithelial cells, while the darker areas show epithelial cells where cilia have not yet formed."