High And Mighty: E. coli Biofilm

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Submitted by Ronn Friedlander in the Aizenberg Biomineralization and Biomimetics Lab at Harvard University

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Ronn Friedlander
Aizenberg Biomineralization and Biomimetics Lab
Scanning Electron Microscope with Secondary Electron Detector

"This image shows a community of E. coli forming what is known as a biofilm. The cells grow as a multicellular assemblage and form complex architectures. I was studying various structural components of E. coli biofilms and some earlier findings led me to investigate the roles of certain matrix genes by generating mutants. I combined one particular mutant with wild-type cells and together, they formed the largest biofilm I’d yet seen. This is an image of one of the tallest parts of the biofilm."