Connecting Synapses with Neuronal Development


Submitted by Robert Luck in the Tye Lab at the Picower Institute for Learning and Memory at MIT


"These are neuronal cells that I isolated from the hippocampus (a brain region) of mice. I stained actin (red), which is a component of the cytoskeleton to see the shape of the cell as well as synapsin (green dots). Synapsin is a protein occurring in synapses. I tried to establish this staining as well as a way to quantify the amount of synapses per neuron to later study the effect of two signaling-molecules on the formation of synapses in vitro."