Integrin Expression in a Pancreatic Tumor

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Submitted by Patrick Murphy in the Hynes Lab at the Koch Institute

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This image shows iineage marking of individual cells within a pancreatic tumor. The marker shows cells which have been modified to alter their expression of integrins, the proteins which mediate adhesion to the extracellular matrix. We aim to understand the contribution of the integrins involved in tumor growth and metastasis.