Stress, Starvation, and Survival: Autophagy in Action

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Submitted by Sandhya Sanduja in the Gupta Laboratory at the Whitehead Institute for Biomedical Research

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When cells are starved for nutrients, they start a ‘self-eating’ process called autophagy. The bright green puncta or autophagosomes as they are called, represent centers inside the cells where cellular components are engulfed and degraded. This provides an internal supply of nutrients and helps cells to survive during starvation. I am studying how autophagy helps cancer cells survive during stress.