Nanoparticles Target Glioblastoma

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Submitted by Fred Lam of the Floyd Lab in the Koch Institute for Integrative Cancer Research at MIT

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This multiphoton image depicts red fluorescent labelled nanoparticles carrying antitumor drugs that have crossed the blood-brain barrier and are targeting a green fluorescent labelled human glioblastoma brain tumor that was implanted and grew in the brain of a mouse. We are now conducting in vivo trials using these particles to deliver combination therapies to mice containing brain tumors in hopes of finding novel and more effective therapies of treating glioblastoma.