Calling the Shots 3

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row of three particles with dye visible inside

Morteza Sarmadi, Christina Ta, Robert Langer, Ana Jaklenec

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row of three particles with dye visible inside

This image shows hollow core-shell microparticles for long-term antigen delivery for vaccination and cancer immunotherapy. The images show distribution of dye (blue) inside the core of a cubic microparticle. Particles are made from biocompatible polymers (PLGA) and are almost half a millimeter. These particles have a cap-base structure. The cap contains a red fluorescent component making it look red. A secondary fluorescent dye (blue) is encapsulated inside the cap. Dye distribution over incubation (interaction with water) has made smile faces--sad to happy to excited, from left to right (showing what a grad student goes through from submission to acceptance of a paper!!)