Up Close and Personal with a Biomimetic Polymer4

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cryo-E-M view of a hydrogel mesh

Sufeng Zhang, Amy Jin, Robert Langer, Giovanni Traverso

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cryo-E-M view of a hydrogel mesh

This image shows the interior structure of a hydrogel at nanoscale. This material was designed to deliver drugs in a targeted way to inflamed regions in the human gut. The network of nano-sized particles with thread-like connections makes it look like “grapes on a vine”; this potentially mimics the mucus network in healthy mucosa and protects the gut.