T cell Quorum Crowd

T cell Quorum Crowd

Submitted by Sudha Kumari of the Irvine Laboratory at the Koch Institute

MIT Department of Biological Engineering, MIT Department of Materials Science and Engineering, Koch Institute at MIT

T cells are the important cells for generating proper immune response. For a coordinated response, they talk to each other, but only very briefly, and this process has been extremely difficult to catch because T cell contacts are very short lived. Using an artificial platform (red dots), human blood T cells are forced to form a stable bunch (each cell represented in different color) to be able to interrogate and understand how they communicate with each other during immune response. The image presents a tool to pursue my aim of studying T cell-T cell contacts.

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